Thursday, December 24, 2015

Congress Just ENDED THE BAN On Medical Marijuana

NEWS: Please do share this information as Mainstream Media has not picked up this story.  There are many suffering only because they still believe that although their state has approved medical marijuana that the federal government will not allow them to use this most effective means to regain health.

The federal ban on medical marijuana is finally a thing of the past. Slipped inside a major budgetary spending bill that was purported to prevent the government from shutting down, is an interesting earmarked section that finally lifts the federal ban on medical marijuana.
The relevant excerpt of bill H.R. 83 text reads as follows:
“Sec. 538. None of the funds made available in this Act to the Department of Justice may be used, with respect to the States of Alabama, Alaska, Arizona, California, Colorado, Connecticut, Delaware, District of Columbia, Florida, Hawaii, Illinois, Iowa, Kentucky, Maine, Maryland, Massachusetts, Michigan, Minnesota, Mississippi, Missouri, Montana, Nevada, New Hampshire, New Jersey, New Mexico, Oregon, Rhode Island, South Carolina, Tennessee, Utah, Vermont, Washington, and Wisconsin, to prevent such States from implementing their own State laws that authorize the use, distribution, possession, or cultivation of medical marijuana. Sec. 539. None of the funds made available by this Act may be used in contravention of section 7606 (“Legitimacy of Industrial Hemp Research”) of the Agricultural Act of 2014 (Public Law 113-79) by the Department of Justice or the Drug Enforcement Administration.”
Cassandra Fairbanks, of the Bipartisan Report, notes that “The measure allows states to implement their own policies regarding medical marijuana, meaning the Department of Justice is now barred from interfering with state medical cannabis laws.”

“For a long time,” Fairbanks explains, “the federal government refused to respect the will of the voters in states with legalized medical marijuana, leading to raids and arrests of doctors, growers, and dispensaries.”

This bill was sponsored by Democrat representatives Dana Rohrabacher and Sam Farr. We reported on its passage last year, that was on a temporary basis. But over the summer it was approved over the summer by the House, with 242 votes to 186.

Finally, “the Senate Appropriations Committee subsequently passed the same amendment sponsored by Democratic Senator Barbara Mikulski, by a vote of 21 to 9.”

“The renewal of this amendment should bring relief for medical marijuana patients and business owners,” Michael Collins, Deputy Director of National Affairs for the Drug Policy Alliance said. “For decades Congress has been responsible for passing disastrous drug laws. It’s encouraging to see them starting to roll back the war on drugs by allowing states to set their own medical marijuana policies.”

Earlier this year, two congressmen just filed two separate House Bills on Friday that together would legalize marijuana at the federal level. That means an effective end to the U.S. government’s prohibition policy on the plant.

Representative Jared Polis (D-Colorado) recently introduced the Regulate Marijuana Like Alcohol Act. This Bill proposes just what it sounds like. Marijuana would be legal, but regulated like alcohol. The Bill would completely remove marijuana from the Controlled Substances Act’s schedules.

The Drug Enforcement Administration would no longer have any say or oversight in policing and regulating the plant. Instead, the Bureau of Alcohol, Tobacco, Firearms and Explosives, would handle regulation of legal marijuana in the same way they regulate alcohol.

Representative Earl Blumenauer (D-Oregon) also introduced the separate Marijuana Tax Revenue Act, which imposes a federal excise tax for regulated marijuana. While that might sound like a huge bummer to marijuana users, it provides a big incentive for politicians to make a progressive move on legalization.

States could still enact their own, individual prohibitions, but the federal ban that exists today would be gone.

Four states as well as the District of Columbia have completely legalized recreational marijuana. Washington DC still prohibits the sale of the plant, however. But beyond that, there are 23 states that have legalized marijuana for medical purposes. Proponents of legalization say it is only a matter of time before there is federal legalization… so what better time than now?

“While President Obama and the Justice Department have allowed the will of voters in states like Colorado and 22 other jurisdictions to move forward, small business owners, medical marijuana patients, and others who follow state laws still live with the fear that a new administration — or this one — could reverse course and turn them into criminals,” Representative Polis explained in a statement released on Friday.

“It is time for us to replace the failed prohibition with a regulatory system that works and let states and municipalities decide for themselves if they want, or don’t want, to have legal marijuana within their borders.”

Representative Blumenauer said that the federal prohibition of marijuana has been “a failure” and a profound waste of tax dollars that have needlessly ruined lives.

“As more states move to legalize marijuana as Oregon, Colorado, Washington and Alaska have done,” Blumenauer added, “it’s imperative the federal government become a full partner in building a workable and safe framework.”

(Article by M. David and Jackson Marciana)

Saturday, March 7, 2015

Phytocannabinoids in the Treatment of Melanoma

Study: Cannabinoids Found in Cannabis May Decrease the Viability of Melanoma Cells

An in-vitro and in-vivo study published in the Journal of Investigative Dermatology in February 2015 found that treatment with delta-9-tetrahydrocannabinol (THC) and cannabidiol (CBD) helped to decrease the viability of melanoma cells.

Cells perform autophagy, a process designed to clean out intracellular debris (e.g. old cell parts [organelles], proteins that are no longer needed, etc.) with the help of lysosomes (organelles that contain enzymes that help to break down proteins, fats, sugars, DNA and RNA building blocks, etc.). Previously collected evidence has shown that in the first phases of cancer development, autophagy is useful in helping to prevent cancerous growth. However, in later stages, autophagy may actually contribute to the formation of cancer by providing resources to cancer cells that help in maintaining survival. In this study, researchers explored whether or not cannabinoids could induce apoptosis (i.e. programmed cell death), and what role autophagy played in this induction, in melanoma cells.

What is Melanoma?

Melanoma is a type of skin cancer, caused by an overproliferation of abnormal melanocytes (cells of the skin that produce melanin, a skin pigment), and is often the result of damage caused by the sun’s UV rays. Although cell abnormality begins in the skin, in later, more advanced stages, cancerous cells can metastasize (i.e. invade distant organs), causing extensive damage and, if uncontrolled, death.
Other types of skin cancer include basal cell carcinoma (BCC) and squamous cell carcinoma (SCC), and melanoma. Although melanoma cases make up only 2% of skin cancer cases, due to the fact that death as a result of BCC is highly unlikely and as a result of SCC is fairly unlikely given that skin lesions grow large and painful (helping in early diagnosis), melanoma is the leading cause of skin cancer deaths. According to the American Cancer Society, in 2014, about 76,100 new melanoma cases were expected to be diagnosed, and about 9,710 people were expected to pass away as a result of melanoma.

In men, melanoma most commonly occurs on the chest and back, and in women, the most common site is the legs. Melanoma is also frequently found on the neck and face.

Skin cancer is much more common in individuals with lighter skin, who have less melanin. However, it is vital that individuals with darker skin tones also be regularly monitored by their health care provider for skin cancer (because it is often assumed that individuals with darker skin will not get skin cancer, when indeed present, the skin cancer is often diagnosed at a late stage, when chances of remission [i.e. cancer non-detectable] are less likely).

Melanoma cases have been rising over the past 30 years. While new discoveries are helping to increase success in the treatment of melanoma, some patients do not respond. Therefore, development of novel treatment options are imperative in helping to increase remission rates for patients with melanoma, especially since melanoma cases are increasing.

How Can You Detect Melanoma?

The most effective way to detect melanoma is to attend annual visits with your dermatologist, who will monitor any unusual or new growths and perform biopsies on skin lesions that have the potential of being skin cancer. Individuals with a family history of melanoma should especially make sure to schedule and attend these yearly visits.

In between visits, it is important to self-monitor your skin (using another person’s help for locations that are hard to see yourself, if possible). Make sure to check all of your skin, including behind your ears, the palms of your hands and soles of your feet, between fingers and toes, under nails, on your scalp, eyelids, and around your genitals and anal region. Frequent self-monitoring will make it easier to notice when a growth seems unusual.

You can use the following guidelines to determine whether or not a mole or patch may need further evaluation by a health care provider:
  • A is for Asymmetry: One half of a mole or birthmark does not match the other.
  • B is for Border: The edges are irregular, ragged, notched, or blurred.
  • C is for Color: The color is not the same all over and may include shades of brown or black, or sometimes with patches of pink, red, white, or blue.
  • D is for Diameter: The spot is larger than 6 millimeters across (about ¼ inch – the size of a pencil eraser), although melanomas can sometimes be smaller than this.
  • E is for Evolving: The mole is changing in size, shape, or color.
  • Other warning signs are:
    • A sore that does not heal
    • Spread of pigment from the border of a spot to surrounding skin
    • Redness or a new swelling beyond the border
    • Change in sensation – itchiness, tenderness, or pain
    • Change in the surface of a mole – scaliness, oozing, bleeding, or the appearance of a bump or nodule
If you find a spot that may be abnormal (in accordance with the above guidelines, or unusual/different from your other skin markings in any other way) make an appointment with your dermatologist. Sometimes skin lesions look a little strange, but end up being benign (i.e. not harmful), but the only way to be certain is to visit your dermatology-trained health care provider. Catching melanoma early, before it has the potential to spread to other organs, is essential in increasing chances of remission and decreasing chances of death as a result of melanoma.

Results of the Study

Studying human melanoma cells in-vitro (i.e. outside of the body), researchers found that administration of THC helped to increase melanoma cell death by way of autophagy-dependent apoptosis, possibly by way of the following pathway:
  • THC leads to creation of a fat called sphingolipid ceramide.
  • Sphingolipid ceramide leads to (1) stress on the endoplasmic reticulum (ER; the smooth ER is a part of the cell involved in lipid and carbohydrate metabolism, as well as detoxification, and the rough ER is a part of the cell involved in protein synthesis) and (2) prevention of the Akt/mTORC1 signaling pathways (which prevent apoptosis by inhibiting autophagy, and lead to increased protein production, helping to keep cells alive and functioning properly) through activation of the protein TRIB3.
  • This stress and prevention of pathways leading to increased cell survival may lead to increased death of melanoma cells.
The researchers note, “when lower doses of THC are combined with CBD the anti-tumour effect was enhanced in vitro”. While the use of THC alone helped to decrease melanoma cell survival, use of a caspase inhibitor (i.e. an agent that prevents activation of enzymes that induce apoptosis) helped to increase melanoma cell death even further. Importantly, while THC helped to increase cell death in melanoma cells in a dose-dependent manner (i.e. the higher the concentration used, the more cell death that occurred), there was no increase in cell death in normal melanocytes (up to a THC concentration of 6 µM, which is beyond the concentration needed to induce cancer cell death). Therefore, THC treatment destroyed abnormal/cancerous melanocytes, but, importantly, did not destroy normal cells.

Using mice as models for humans with melanoma, researchers evaluated the use of whole-plant cannabis extract with a 1:1 ratio of THC (similar to Sativex) for the treatment of BRAF wildtype melanoma, which is a form of the disease that has limited treatment options. They found that treatment with the 1:1 THC:CBD extract, at a concentration of 1 µM of each, helped to decrease melanoma cell survival, even more than treatment with THC alone. In contrast, temozolomide, a chemotherapy agent used to treat glioblastoma multiforme, had a small effect. According to the researchers, “Collectively these data suggest THC and Sativex-like are more effective than temozolomide in terms of apoptosis induction and anti-tumour response, further validating the therapeutic relevance of cannabinoid treatment for melanoma.”

These results are particularly impressive given that alkylating agents, like temozolomide (that work by damaging DNA), although effective in reducing cancer cell growth/increasing cancer cell death in certain types of cancer, can have severely harmful side effects, which may include the formation of new types of cancer. The use of cannabinoids, on the other hand, has been shown to be generally well-tolerated with minimal negative side effects.

Additionally, according to the researchers, “CBD induces apoptosis via the production of reactive oxygen species [agents that cause cell and tissue damage] and caspase activation in cancer cells… indicating THC and CBD engage different molecular machinery which cooperate to promote tumour cell death.”


These results add to a growing body of evidence that suggests that cannabinoids may be useful for the treatment of various types of cancer (breast, prostate, lung, skin, pancreaticbrainbladder cancer, leukemia). Specifically, they demonstrate that the use of phytocannabinoids may be useful in the treatment of both BRAF-mutated and BRAF-wildtype (i.e. “normal” BRAF) melanoma. This is especially important for patients with BRAF-wildtype melanoma, given the limited treatment options for this form.

In contrast to alkylating agents used in chemotherapy treatment, phytocannabinoids have so far shown to have a highly favorable safety profile, which provides an additional rationale for increasing research on whether or not cannabinoid therapies are effective for the treatment of cancer, including melanoma.

Source and Full Story:

Water-Wise Cultivation Workshop - Nevada County California

Workshop focuses on sustainable cannabis cultivation

"California’s current “Green Rush” has attracted many farmers to grow medical marijuana, or cannabis, in Nevada County where land is relatively cheap, water seems plentiful and the sun shines 250 days out of the year. By some accounts, the county may be producing $50 million to $600 million worth of cannabis annually, according to event organizers.
“While most of the attention surrounding cannabis cultivation has focused on economic, medical or social issues, we call upon our community to make sure that the negative environmental impacts to the Yuba River are not overlooked,” said Caleb Dardick, executive director of the South Yuba River Citizens League.

“Every new economic ‘rush’ from hydraulic mining to clear-cutting has had profound impacts on the Yuba River over the past 160 years. Maybe this time we can find collaborative, local solutions to protect this watershed we all love so much,” said Hank Meals, local historian, author and member of SYRCL’s Community Advisory Board.

On March 21, the public is invited to attend “Growing Green for the Yuba,” SYRCL’s daylong informational workshop, to learn from local and regional experts about practices for cultivation that will safeguard the Yuba watershed.

The presenters will address a variety of topics, including water management systems, soil health and nutrient use, pest management and alternative energy.

There will also be two panel discussions focused on “Local Growers Issues” and “Local Grow Shop Issues,” including local and statewide regulations and products that are available locally.

“With this event, we hope to draw attention to the cumulative impact of small growers across our watershed, which is already starting to have a visible impact on the Yuba and its tributaries from dry creek beds to toxic algae blooms,” said Rachel Hutchinson, SYRCL’s science director.

“People will come away from this workshop with the tools they need to grow cannabis in a way that does not harm the water quality, fish and wildlife we cherish here in the Yuba watershed,” said Amigo Bob Cantisano, a renowned leader in the organic gardening movement and a confirmed speaker at the workshop. “If all growers agreed to farm using environmentally sustainable methods, we can foster a truly ‘green’ Green Rush in the foothills.”

“As responsible business owners in the Yuba, we want to encourage cannabis cultivators to be sustainable. There should be no controversy between thriving farms and a healthy river,” said Darlene Markey, owner of Sweetland Garden Supply and a sponsor of SYRCL’s workshop.
SYRCL is not taking a position — pro or con — on cultivation, organizers said.

“We’re simply saying that if you are going to grow, adopt best practices and do it in a way that doesn’t harm our waterways,” said Holly Mitten, SYRCL vice president and chair of the Marijuana is a Watershed Issue Committee.

The “Growing Green for the Yuba” workshop is sponsored by Forever Flowering, Vital Garden Supply, Sweetland Garden Supply and Americans for Safe Access-Nevada County."



Friday, January 2, 2015

What Helps With What?

A quick visual overview of the many benefits of cannabis.
The medicinal value compliments our bodies' own abilities.
Help us help others research the facts.

To learn more about the many strains of cannabis please be sure to visit

Thursday, January 1, 2015

121 Studies Cannabinoids Kill Cancer cells

Compilation list of the 121 studies of cannabis kills cancer cells:

Here's 121 studies proving Cannabinoids (THC & CBD) KILL CANCER cells.

Cannabis kills Tumor
Cannabis Cures Colorectal Cancer:
Cannabis Cures Uterine, Testicular, and Pancreatic Cancers:
Cannabis-derived substances in cancer therapy and anti-tumour properties:
Cannabis Cures Brain Cancer:
Cannabis Cures Mouth and Throat Cancer:
Cannabis Cures Breast Cancer:
Cannabis Cures Lung Cancer:
Cannabis Cures Prostate Cancer:
Cannabis Cures Blood Cancer:
Cannabis Cures Skin Cancer:
Cannabis Cures Liver Cancer:
Cannabis Cures Cancer in General:
Cannabinoids in intestinal inflammation and cancer:
Cannabis use and cancer of the head and neck: Case-control study:
Cannabis THC at high doses in area, inhibits cholangiocarcinoma cancer:
Targeting CB2 cannabinoid receptors as a novel therapy to treat malignant lymphoblastic disease
Marijuana kills cancer cells:
Cannabis Treatment in Leukemia:
Cannabinoids and the immune system:
Cannabis partially/fully induced cell death in Cancer:
Cannabis treatment of translocation-positive rhabdomyosarcoma:
Cannabis Induces apoptosis of uterine cervix cancer cells:
Cannabis treatment in lymphoma:
Cannabis kills cancer cells:
Cannabis regulator of Neural Cell Development
Cannabis treatment of Melanoma:
Cannabis treatment for Thyroid Carcinoma
Cannabis treatment in Colon Cancer:
Cannabinoids in intestinal inflammation and cancer.
Cannabinoids in health and disease:
Cannabis a neuroprotective after brain injury
Cannabis inhibits Cancer Cell Invasion:



This is a great article that may get a lot of us thinking.  It certainly did for me.  A big thank you to the Skunk Pharm Research, LLC for this information.  Hope you all will check out their website.

Holy Annointing Oil and Holy Shit.
Holy Anointing Oil and Holy Shit.

Hi ya’ll, please doooo try this at home because the results are beyond impressive! They are startling.
Not only does it provide psychoactive free rapid pain relief used as a topical, but with slight modifications, switch hits sublingually to combine pain relief, with a general uplifting to the spirits and relaxing of the body.

Head effect varies from noticeable in high tolerance patients to blasted in low tolerance patients.
Body effect varies from relaxed, to couch locked, depending on tolerance and dosage.

Who knows how old the recipe actually is, because the surviving recipe is from Exodus 30, verses 22-30:
22 Then the LORD said to Moses, 23 “Take the following fine spices: 500 shekels of liquid myrrh, half as much (that is, 250 shekels) of fragrant cinnamon, 250 shekels of fragrant cane, 24 500 shekels of cassia – all according to the sanctuary shekel – and a hin of olive oil. 25 Make these into a sacred anointing oil, a fragrant blend, the work of a perfumer. It will be the sacred anointing oil. . . .
30 “Anoint Aaron and his sons and consecrate them so they may serve me as priests.”

FirstChurchof the Magi has since risen, who considers the Holy Anointing Oil a sacrament, and more of their thoughts may be found at:…-holy-anointing.

From the standpoint of process, the perfumers of the time, would have put cinnamon bark, cinnamon leaf, and cannabis bud in olive oil and water. Boiled the water away, strained the oil, and used it in that form.

Eloquentsolution discovered Holy Anointing Oil on another forum pre skunk pharm, and did the math, discovering that the formula called for about 15 ounces of land race cannabis per liter of olive oil, regardless of what else was in it. Whoa!

After reading her post on the subject, how could I resist corroborating with making a batch and checking it out? Since they were using the landrace cannabis of the time, its actual potency is of course conjecture, but there are some clues in the process that they used and the MSDS on cinnamon oil, which says that greater that a 1% solution will burn our skin.

Cutting to the chase, we needed essential oils of the additives to maintain continuity of formula, since we were already using essential oils of cannabis.  I found the cinnamon bark oil, cinnamon leaf oil, and myrrh gum from and we have been happy with their service every since, though they aren’t certified as food grade.  That doesn’t mean that they are not food grade, only that it isn’t assured, and they are of course suitable for topical Holy Anointing Oil.
Alternative bulk sources for food grade essential oils for use in oral medications are: 

and right here in Portland, Oregon

I made a batch with olive oil, but Eloquentsolution switched her formula from olive oil, to coconut oil, because of coconut oils other salubrious qualities, among them medium chain triglycerides for faster absorption and more rapid passing of the blood brain barrier.  Another thought provoking coconut attribute, is that coconut milk is the only natural substance discovered thus far, that can double as blood plasma in humans.

Both of our first batches were impressive, but as Eloquentsolution’s was better, we’ve used coconut oil ever since.  She also continued to experiment and developed our current formulas for both Holy Anointing Oil Oral, and Holy Anointing Oil Topical, which have different ratios, and the topical also contains Emu oil.

The combination of the cannabis oil and the other ingredients seems to speed up and intensify the results and the whole appears greater than the sum of the parts.

At about the same time, I was also working on my cinnamon Cannapop lollypop recipe, and used a 50% mixture of cannabis oil and Cinnamon candy flavoring oil, from

Because the mixture was so tasty, some of the skunk pharmers, who dropped by, started asking for a taste, and asked for it by the name of, “that good shit.”  I therefore named the mix GS, for “Good Shit.”

One day I decided to see if Cinnamon candy flavoring oil would ameliorate the slight after taste of HAO sublingual, and when it was successful, I named the mix, “Holy Shit”, or HS.

Here are the formulas, both fractionally and in decimals.

Holy Anointing Oil Oral:
1                  Part Cannabis Oil
1/3               Parts virgin unrefined Coconut oil
1/15th           Part Cinnamon Leaf oil
1/15th           Part Cinnamon Bark oil
1/30th           Part liquid Gum Myrrh
IE:      1/3 = .3 (.33333333333)
1/15 = .07 (.066666666666)
1/30 = .03 (.033333333333)
10      grams BHO Cannabis oil
3       grams Coconut oil
.7       grams Cinnamon Bark oil
.7       grams Cinnamon Leaf oil .
.3       grams Myrrh Gum
Holy Anointing Oil Topical:
10      grams BHO Cannabis oil
8         grams Coconut oil
.7       grams Cinnamon Bark oil
.7       grams Cinnamon Leaf oil .
.7       grams Myrrh Gum
1         grams Emu oil
*         Optional Arnica Montana and/or Jojoba oil
Holy Shit:
10      grams BHO Cannabis oil
3        grams Coconut oil
.7       grams Cinnamon Bark oil
.7       grams Cinnamon Leaf oil .
.3       grams Myrrh Gum
1         gram Cinnamon candy flavoring oil

We make these oils, by adding the other ingredients to the decarboxylated cannabis oil, while the oil is above 82C/180F, and stirring until well mixed.  Bottle and use as is.

For decarboxylation instructions, check out the tab on our home page, under that name.

Bon appetite!


Decarboxylation Tips

Decarboxylation -  

When making cannabis oil for treating late stage cancer it is important to understand decarboxylation. Cannabis in raw/unheated form is primarily THCA, which converts to active THC through heat and time.

While some very slow and gradual decarboxylation does occur at temperatures as low as room temp during drying and curing stages of weed preparation it is not until higher heats are encountered that all THCA is converted to THC. If you are making cannabis oil you need to make sure the oil is cooked sufficiently to complete full decarb.

Raw cannabis is very beneficial and cannabinoid acids like THCA, along with naturally present terpenes, are believed to be very beneficial with possible anti cancer properties. However, it is active THC, and CBD, that has the majority of clinical and anecdotal evidence supporting its cancer killing effects. So, based on what is currently known, cannabis oil that is most potent in THC content is likely going to be the most potent medicine for curing cancer. Raw cannabis in the form of juices and unheated oils are beneficial too and would make a great addition to someone's treatment, but should not replace cooked cannabis oil, and often require much larger quantities for therapeutic value. Raw or partially cooked oils will contain a wider range of components including cannabinoid acids and terpenes, which are lost when oils are fully cooked, but THC is the most essential cannabinoid for fighting cancer so make sure you decarb your medicine properly to maximise its potency.

The Rick Simpson method only guarantees partial decarb from the rice cooker stage, and while full decarboxylation can be achieved with the use of a coffee warmer or candle warmer it can take some time to complete this process and other gentle heating devices may not be hot enough. Many of the solvents used have boiling points below the optimum temps for full and rapid decarb. If you do not have a coffee/candle warmer, of even if you do, it is recommended to put your oil in the oven at 110 degrees Celsius for about an hour (optimum temperature range is 110c to 130c/230F to 266F).

  Visible bubbling will cease when the solvent and water, along with volatile terpenes, are boiled off. But you will see very small pin prick explosions on the surface of the oil during decarboxylation. When this has ceased and there is no activity on the surface of the oil at temps of 110c or above, then you know that decarboxylation is complete. While you want to ensure that temperature does exceed 110 degrees Celsius for decarb, it is also advised to stay below 140 as temps above 140 can lead to a loss of THC through vaporisation or degradation to CBN (vaporising of THC occurs from 157c).

In an ideal world everyone would have access to both raw and cooked cannabis in a well controlled manner, but in this world where oil making can be expensive and risky it is best to make sure your medicine is as potent as it can be to maximise its potential.

Source: A Friend